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Viagra can teach us a lot about treating rare diseases

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In June 1993, David Brown was exasperated. For eight years he had been developing a drug that was supposed to treat angina, but early clinical trials showed it wasn’t having enough of an effect to make it into a commercial success. His employer, Pfizer, gave him three months to turn the project around. A few weeks later, Brown heard some unusual news from a group of Welsh men involved in a...

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